Parp Inhibitor Side Effects

Your doctor may temporarily or completely stop treatment if you develop pneumonitis.

Parp inhibitor side effects.

Common side effects of parp inhibitors include. Fast heartbeat hives itching skin rash irritation joint stiffness or swelling redness of the skin swelling of the eyelids face lips hands or feet troubled swallowing. Lynparza olaparib is an inhibitor of the mammalian polyadenosine 5 diphosphoribose polymerase parp enzyme used as monotherapy in patients with deleterious or suspected deleterious germline brca mutated advanced ovarian cancer who have been treated with three or more prior lines of chemotherapy. Parp inhibitor associated gi toxicity.

Bloody or cloudy urine. Drugs that inhibit parp1 cause multiple double strand breaks to form in this way and in tumours with brca1 brca2 or palb2 mutations these double strand breaks cannot be efficiently repaired leading to the death of the cells. Feeling or being sick tiredness diarrhoea indigestion and taste changes headaches and dizziness changes to the way your liver and. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them.

Acid or sour stomach. Pneumonitis may lead to death. Poly adp ribose polymerase parp inhibitors are a class of oral anticancer medications that have the. Tell your doctor if you have any new or worsening symptoms of lung problems including shortness of breath fever cough or wheezing.

The common side effects for all parp inhibitors can include. Managing side effects from parp inhibitors introduction. The most common side effects of parp inhibitors are. Your doctor may do a chest x ray if you have any of these symptoms.

An increased risk of infection bleeding problems tiredness and breathlessness due to a drop in the number of blood. Parp inhibitors cause fewer and less serious side effects than some other cancer treatments. Inhibitors of one enzyme parp 1 are being studied in the treatment of breast cancer. What are side effects of lynparza.

Vomiting fatigue upset stomach this includes possible diarrhea constipation and abdominal pain various bone marrow related side.